Active substance: simvastatin ;
1 tablet covered with film-coated, containing 10 mg or 20 mg or 40 mg of simvastatin;
Excipients: lactose monohydrate, pregelatinized starch, butylhidroksianizol (E 320), citric acid anhydrous, ascorbic acid, corn starch, microcrystalline cellulose, magnesium stearate;
film shell: hypromellose, talc, propylene, titanium dioxide (E 171).
Pharmacological group .
Lipid-lowering agents, monocomponent. Inhibitors of HMG-CoA reductase.
Treatment of primary hypercholesterolemia or mixed dyslipidemia as an adjunct to diet when the response to diet and other non-drug treatments (eg exercise, weight reduction) is inadequate.
Treatment of homozygous familial hypercholesterolemia as an adjunct to diet and other lipid-lowering treatments (eg lipid apheresis low density), if such treatment is not sufficient.
Reduction of cardiovascular mortality and morbidity in patients with manifest atherosclerotic cardiovascular disease or diabetes with normal or elevated cholesterol levels, as an additional treatment for the correction of other risk factors and to other cardioprotective therapy (see. Section "Pharmacological properties").